Cell dissociation is the method of using trypsin, a proteolytic enzyme that breaks down proteins, to dissociate cells from the vessel in which they are cultured. When added to cell culture, trypsin breaks down the proteins, which enable the cells to adhere to the vessel. It is often used to pass cells to a new ship. It helps to improve the isolation efficiency with high cell viability.
The global cell dissociation market size was valued at USD 230.2 million in 2019 and projected to reach USD 546 million by 2027, growing at a CAGR of 12.1% during the forecast period, 2020-2027. The significant factors are the growing demand for advanced tissue disassociation enzyme products and increasing R&D investments. Additionally, the increasing focus on research and development in the pharmaceutical industries will spur the global cell dissociation industry in the future periods. Furthermore, the growing public-private funding for cell dissociation activities and rising funding for cancer research are expected to witness remarkable growth of cell dissociation. The rising investment in life science industries with an increase in research on chronic diseases is expected to propel cell dissociation demand over the coming years.
Moreover, the upsurge in demand for enzyme dissociation instruments positively impacts the market for cell dissociation in the healthcare industry. Furthermore, the rapid expansion in customer base, rise in the extensive R&D activities at the academic and industrial level, and increasing biomedical applications are fueling the demand for cell dissociation in the healthcare market. Additionally, the growing geriatric population and growing healthcare demands in the developing world propelling the growth of the cell dissociation market across the globe.
The cell dissociation process has tremendous application in stem cell research and regenerative medicines. Due to the advantages of large market size, low market concentration, and gradual maturity of technology applications, cell dissociation products have attracted various enterprises to the layout. The rising investments from multiple government bodies and private players are also stimulating the growth of the market. However, the high cost of soft-tissue procedures can be a restraint to the development of the cell dissociation market.
Based on the product, the global cell dissociation market was segregated into enzymatic dissociation products, non-enzymatic dissociation products, and instruments & accessories. The enzymatic dissociation products segment is estimated to witness the highest growth over the analysis timeframe due to widespread use in the biotechnological process, veterinary medicine, and tissue culture lab. In addition, trypsin is used to treat digestive disorders, cell dissociation, and protein sequencing.
The non-enzymatic dissociation products will grow significantly due to the benefits such as free of animal-derived components, reduces the risk of cellular damage associated with long exposure time, gentle cell disaggregation, and high cell viability.
The global cell dissociation market is categorized into Connective tissue, epithelial tissue, and other tissue based on the tissue. The connective tissue segment is held for a significant market share in 2019 and will gain maximum market revenue by 2027. It is attributable to the rising research on cancer and the increasing prevalence of cancer due to destructive lifestyles.
The epithelial tissue segment is poised to witness significant growth over the forecast period due to widespread tissue culture research and cell biology application.
Based on the Type, the global cell dissociation market is classified into tissue dissociation and cell detachment. The tissue disassociation is expected to be the highest revenue share for cell dissociation during the forecast period. The segment’s growth is primarily estimated to the growing use in tissue culture research and cell therapy applications.
The cell detachment will witness a lucrative growth rate in the estimated period due to maximum cell viability, rapid force, and no need to wash detached cells.
Based on the end-user, the global cell dissociation market is segmented into pharmaceutical & biotechnological companies, Research & academic institutes, and other end users. The pharmaceutical and biotechnology companies centers segment will dominate the global cell dissociation market by 2027 due to the surge in demand for enzyme dissociation products, economic expansion, and government focus on broader healthcare policies.
The research and academic institutions accounted for the largest share of the cell dissociation market in 2019 because of the increasing use of enzyme dissociation instruments, increasing cell culture research, and rising research and development expenditure.
The global cell dissociation market is segmented into North America, Europe, Asia Pacific, South America, and Middle East & Africa by geography. North America is estimated to project considerable growth over 2020-2026. It is owing to advents in technology, the presence of leading industry players offering innovative products, and increasing healthcare expenditure.
The Asia Pacific will record a prominent share of the cell dissociation market by 2027. Due to the increasing adoption of enzyme dissociation technologies, we are continually improving healthcare infrastructure in the region and mounting healthcare expenditures in rising economic powerful countries such as India and China.
Merck KGaA, Stemcell Technologies, Thermo Fisher Scientific, GE Healthcare, Roche Holding AG, Bacton Dickinson and Company, Miltenyi Biotec, HiMedia Laboratories, and PAN-Biotech are the key players in the global cell dissociation market.
By Product
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