Chemicals & Materials

Global Preparative and Process Chromatography Market

January 24, 2022
ID: SR/CH-51
Format:Pdf
Pages:220

Global Preparative and Process Chromatography Market, By Type (Process Chromatography and Preparative Chromatography), By Product (Solid Supports and Reagents, Resin {Affinity Resins, Ion-Exchange Resins, Protein A Resins, Hydrophobic Interaction Resin, Mixed-Mode/Multimode Resin}, Columns {Pre-Packed Columns and Empty Columns}, Systems {Liquid Chromatography Systems and Other Chromatography Systems}), By End-User (Biotechnology and Pharmaceutical Industries, Food and Nutraceutical Industries, Academic Research Laboratories and Other), By Region (North America, Europe, Asia-Pacific, South America and The Middle East& Africa)-Global Forecast to 2028.

Description

The global preparative and process chromatography market scope was calculated at USD 7.75 billion in 2021 and is predicted to achieve USD 13.7 with a CAGR of 11.65% from 2022 to 2028. Large-scale integration of liquid chromatographic strategies in downstream processing, technological improvements, and increased need for preparative techniques have accelerated the development in this space. Growing demand and support of monoclonal antibodies in the pharmaceutical and biotechnology industries is expected to fuel this space’s growth throughout the forecast period.

What are Preparative and Process Chromatography?

The preparative and process chromatography processes are primarily used in gas chromatography, liquid chromatography (including supercritical fluid chromatography), and HPLC (High-Performance Liquid Chromatography). Process chromatography arrives into the picture post preparative chromatography. It explores the purification process conducted during preparative chromatography. An ever-increasing usage of chromatography techniques in the nutraceuticals and food industry is predicted to maintain high hopes for the preparative and process chromatography market.

Growth Drivers

Increasing awareness about improvements in Preparative and Process Chromatography

Market players such as manufacturers of chromatography devices, consumables, accessories, and service providers are growing awareness about the improvements in preparative and process chromatography. In 2020, PREP 2020 — 33rd International Symposium on Preparative and Process Chromatography held in the United States on 31 May 2020. The PREP 2020 is the longest-running & recognized international scientific conference and exposition driving the field of Preparative and Process Chromatography, organized by expert scientists and engineers for the detachment science practitioner. The seminar addressed the latest scientific and technological advances, essential and emerging applications and techniques, and challenges and solutions in all elements of Preparative and Process Chromatography, Ion Exchange, Adsorption/Desorption Processes, and Related Separation Techniques. The emphasis of this conference is the development, design, optimization, and operation of chromatographic processes and technology for a broad range of applications.

Opportunities

The rising market for monoclonal antibodies

Preparative and process chromatography creates a critical role in refining monoclonal antibodies (mAbs). mAbs showcase immense possibilities as biopharmaceuticals to treat an expansive range of illnesses. With such promising opportunities, major biopharmaceutical players such as Pfizer Inc., Novartis International AG, Boehringer Ingelheim International GmbH, Amgen Inc, and Samsung Bioepis have raised their emphasis on mAbs. The increasing number of mAbs supported by regulatory bodies is also a critical element supporting the growth of the mAbs market.

Restraints

The increased expense of devices

Preparative and process chromatography systems are expenses at a premium because of the elements and technologies. Small- & medium-sized enterprises in the oil & gas, food & beverage, biotech & pharmaceutical industries, and research and academic institutions demand multiple such systems in their operations. Hence, the capital expenditure expended on these systems enhances immensely. Moreover, academic research laboratories discover it challenging to afford such systems, as they have maintained budgets. The maintenance costs and other indirect expenditures result in an overall increase in these instruments’ total cost of ownership. They restrict the adoption of chromatographic accessories & consumables among price-sensitive end-users, such as research laboratories, academic institutes, and small companies.

Pre Covid-19 Impact on Global Preparative and Process Chromatography

Before the Covid-19 period, Chromatography plays an important function in numerous pharmaceutical, chemical, and food industries. Environmental testing laboratories normally identify extremely small impurities in waste oil and pesticides, such as PCBs. Chromatography is utilized to test drinking water and monitor air quality. Pharmaceutical industries use this form to collect huge quantities of extremely refined materials and examine the purified compounds for trace impurities. High-performance liquid chromatography is utilized in protein breaks, such as insulin cleansing, plasma fractionation, enzyme purification, DNA fingerprinting, and bioinformatics, which improved the growth of the preparative and process chromatography market.

Covid-19 Impact on Global Preparative and Process Chromatography

During the Covid-19 period, the pandemic has seriously impacted the preparative and process chromatography market. With the increasing threat associated with COVID, investigators are positively dependent on analytical laboratory methods such as chromatography to gain sufficient and efficient strategies for describing the virus and examining potential vaccines and anti-COVID-19 compounds. Chromatography is one of the crucial technologies, mainly in refining biomolecules, including RNA. Analytical devices play a central role in the laboratory work centering on the SARS-CoV-2 virus, including the three major areas of COVID-19-related research — vaccine development, therapeutics expansion, and diagnostic testing.

Post Covid-19 Impact on Global Preparative and Process Chromatography

After the covid-19 outbreak, the commonly used drugs, such as hydroxychloroquine, have witnessed a dramatic surge in demand for the treatment of the COVID-19 virus. Such increased demand for these drugs has shown a massive opportunity for manufacturers of COVID-19 drugs as many advanced countries are scarce of these drugs. The pharmaceutical & biotechnology industry is predicted to notice considerable growth in the future, owing to the need for vaccine and treatment drugs for COVID-19. After the COVID-19 period has positively impacted the process and preparative chromatography market as the separation process and preparative chromatography can be used to analyze ingredients to prepare a vaccine for coronavirus.

Type Segmental analysis

Based on Type Segment, the market is classified into Process Chromatography and Preparative Chromatography. The process chromatography segment is calculated as the largest share of the market. It is mostly due to the increasing production of pharmaceutical products and investments in the pharma biotech industry. Moreover, with the explosion of COVID-19, there has been an increase in demand for vaccines and medicines for treatment, hence driving the demand for process chromatography products.

Product Segmental Analysis

Based on Product Segment, the market is classified into Solid Supports and Reagents, Resin (Affinity Resins, Ion-Exchange Resins, Protein a Resins, Hydrophobic Interaction Resin, Mixed-Mode/Multimode Resin), Columns (Pre-Packed Columns and Empty Columns), Liquid Chromatography Systems and Other Chromatography Systems. The liquid chromatography component accounted for the highest share of 29.11% in 2021, owing to the widespread application across several industries. Some major preparative and process chromatographic techniques, including liquid chromatography (LC), HPLC, and gas chromatography, rely on the type.

End-User Segmental Analysis

Based on End-User Segmental Analysis, the market is classified into Biotechnology and Pharmaceutical Industries, Food and Nutraceutical Industries, Academic Research Laboratories and Other. The pharmaceutical segment accounted for the largest share of 62.64% in 2021, owing to the high use of preparative and process chromatography in drug protection assessment. The demand for developing a good vaccine against the novel coronavirus in a decreased timeframe has introduced individual vaccine approaches, such as viral vector-based vaccines, nucleic acid-based vaccines, and virus-like particle vaccines.

Regional Segmental Analysis

Based on Regional Segment, the market is classified into North America, Europe, Asia-Pacific, South America and The Middle East& Africa. North America maintains the largest revenue share of 32.11% in 2021, followed by Europe. A substantial number of key players, coupled with increasing R&D programs for disease management, has driven the regional market.

Competitors Analysis

The Companies include Thermos Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Bio-Rad Laboratories, Inc., Agilent Technologies, Shimadzu Corporation, Waters Corporation, Novasep Holding S.A.S, Daicel Corporation, Hitachi High-Tech Corporation, Restek Corporation and other prominent players in the global preparative and process chromatography market.

Key Stakeholders

Market research and consulting firms
Preparative and Process Chromatography Market Associations
Local Governments
Regulatory bodies
Preparative and Process Chromatography providers
Suppliers
Retailers

Recent Developments

In 2021, Waters established the Waters Arc Premier System, optimized for chromatographic breaks on 2.5 – 3.5 micron columns.
In 2021, Daicel Chiral Technologies established the CHIRALPAK IK.
In 2021, Novasep and Sartorius Stedim Biotech formed a contract to sell the former company’s chromatography equipment department to Sartorius. This procedure will encourage Novasep to accelerate the growth of its chromatography division by joining a regular leader in the field.
In 2020, Danaher obtained the Biopharma business from General Electric Company’s Life Sciences department, which is now called Cytiva. Captiva is a standalone operational company within Danaher’s life sciences segment.
In 2020, Repligen and ARTeSYN joined into a definitive agreement to obtain the latter company. The addition of ARTeSYN has supported Repligen’s systems delivering in the market.

Scope of the Report

Report Attribute	Details
Market Size Value in 2021	USD 7.75 Billion
The revenue forecast in 2028	USD 13.7 Billion
Growth Rate	CAGR of 11.65 % from 2022 to 2028.
Historical data	2018-2020
Forecast period	2022 – 2028
Region covered	North America, Europe, Asia-Pacific, South America, and Middle East & Africa
Key companies Profiled	The Companies include Thermos Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Bio-Rad Laboratories, Inc., Agilent Technologies, Shimadzu Corporation, Waters Corporation, Novasep Holding S.A.S, Daicel Corporation, Hitachi High-Tech Corporation and Restek Corporation are key players.

Market Modelling

By Type

Process Chromatography
Preparative Chromatography

By Product

By End-User

Biotechnology and Pharmaceutical Industries
Food and Nutraceutical Industries
Academic Research Laboratories
Other

By Region

North America
Europe
Asia-Pacific
South America
The Middle East & Africa

Table Of Contents

Methodology

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Frequently Asked Questions (FAQ):

What is the growth rate of global preparative and process chromatography?

The global preparative and process chromatography market scope was calculated at USD 7.75 billion in 2021 and is predicted to achieve USD 13.7 with a CAGR of 11.65% from 2021 to 2028.

Which type of chromatography is expected to hold the largest share in the preparative and process chromatography market?

The demand for process chromatography is expected to be considerably high in the preparative and process chromatography market.

What are the driving elements of the preparative and process chromatography market?

Elements include the increasing need for insulin and other biopharmaceutical products, increased demand for omega-3 fatty acids, growing awareness about the improvements in preparative and process chromatography, growing food safety problems, and increasing government investments for synthetic biology and genome schemes to help the growth of the market.

What are the challenges noticed in the preparative and process chromatography market?

The shortage of experienced professionals managing preparative and process chromatography coupled with the technical limitations of the technique is the challenge witnessed in the preparative and process chromatography market.

Who are the key players in the preparative and process chromatography market?

The Companies include Thermos Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Bio-Rad Laboratories, Inc., Agilent Technologies, Shimadzu Corporation, Waters Corporation, Novasep Holding S.A.S, Daicel Corporation, Hitachi High-Tech Corporation and Restek Corporation are the key players in the preparative and process chromatography market.

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