The global Serine Protease market size is forecasted to reach USD 4.1 billion with a CAGR of 5.5% over the forecast period, 2022-2028. The growing industrialization, growing focus on cost reduction and resource optimization, and increasing application of serine protease in the food industry such as Dietary Supplements and Nutraceuticals, Pharmaceutical, and Industrial such as detergent leather are the primary factors accelerating the growth of the global serine protease market during the forecast period. Moreover, the growing environmental concern, increasing incidence of diseases, and their versatile application in molecular biology, biofuels will further stimulate the growth of the global serine protease market in the coming years.
Proteases are produced from different sources like plants, animals and microorganisms, but their large-scale production implies microbial community. One of the most essential commercially known enzymes comprised of protease is serine. Serine proteases are diverse enzymes characterized by three critical amino acids, histidine, aspartate, and serine, in the catalytic site. The “serine” in the name of serine proteases refers to the involvement of the catalytic site serine in the catalysis of proteolysis in this category of enzymes. A class of serine proteases, the thrombin-like proteases, including thrombin, tissue plasminogen activator (tPA), and plasmin, are best known for coagulation and inflammation responses.
It is estimated that out of all the commercial enzymes sold every year, proteases consist of 60%, and the most selling one is a serine protease with an average of 89%. Serine is one of the most important commercially available enzymes comprised of proteases, having a broad scope of applications in different industries like detergent, leather and food industries (Dietary Supplements and Nutraceuticals). Serine proteases are resistant to a wide range of changes in temperature and pH and usually do not get denatured by detergents and toxic metals, resulting in the increased demand for serine proteases for industrial purposes across the globe. These serine proteases also have applications in the tannery, wastewater treatment, silver recovery and resolution of amino acids mixtures, as these protease-based detergents have better cleaning dust removal ability. Moreover, the growing demand for eco-friendly products has led the manufacturers to include a natural alternative to chemical ingredients, owing to which serine proteases are gaining popularity for various industrial applications across the globe. Serine proteases are widely used to produce high nutrition protein hydrolysates in the food industry. In addition, the increasing incidence of digestive disorders has increased the demand for serine proteases to treat digestive disorders and food allergies.
The significant increase in the demand for serine protease among various industries, including the leather industry, medical diagnostics, recovery of silver from X-rays, food and feed industry, has stimulated the growth of the global serine protease market in the pre-COVID era. Proteases are one of the most important industrially and academically important groups accounting for around 65% of the annual enzyme market. Due to their widespread applications, many industries have started their production at the commercial level.
The outbreak of the COVID-19 pandemic has partially impacted the growth of the global Serine Protease market in 2021. Many producers report decreased activities in many regions. The reasons for less action vary in the different countries due to various areas like due to the lockdown in many countries, production of serine protease has been abruptly shut down because of the implications of the virus outbreak. Moreover, the outbreak of COVID-19 and its subsequent entry into the Asia Pacific has led to the complete shutdown of various manufacturing and production facilities in the region, resulting in a significant decline in the growth of the global serine protease market.
The growing demand for natural food ingredients in the food and beverage industry is expected to create lucrative opportunities in the growth of the global serine protease market during the forecast period. A rising consumer disposable income and purchasing power leads to a shifting preference for eco-friendly products. Various companies are introducing artisanal & gourmet food products in different forms in terms of economical and premium ranges. These companies are expected to gain lucrative opportunities to capitalize on the premiumization of their product portfolio to bolster their market position due to an increase in globalization and economic growth, which creates enough space for the growth of the global serine protease market in the coming years.
Based on the Application, the global Serine Protease market is categorized into Digestive System, Blood Coagulation System, Complement System, and Others. The Blood Coagulation System segment is expected to hold the highest share in the global Serine Protease market in the coming years. A class of serine proteases, the thrombin-like proteases, including thrombin, tissue plasminogen activator (tPA), and plasmin, are best known for coagulation and inflammation responses. Furthermore, the most important application of proteases in the food industry is in the process of cheese-making. Lactic acid bacteria are used for milk coagulation, an essential feature for yogurt production.
Based on the End User, the global Serine Protease market is segregated into Dietary Supplements, Nutraceuticals, pharmaceuticals, Industrial, and others). The Food industry (Dietary Supplements and Nutraceuticals) segment dominates the global Serine Protease in 2021 and is expected to continue this trend in 2022-2028. Serine Protease is used to fortify soft drinks and fruit juices and as a part of infant food formulations. In addition, serine proteases are also gaining the demand in cheese making. Furthermore, the pharmaceutical and industrial segment is expected to witness significant growth in the global serine proteases market during the forecast period. In the pharmaceutical industry, serine proteases are used to treat digestive disorders and ointment composition, non-woven tissues, soft gel medicinal formulas, gauze and new materials.
The Serine Protease market is characterized by North America, Europe, Asia Pacific, South America, and Middle East & Africa. The Asia Pacific region is expected to dominate the global Serine Protease market in 2021 and continues this supremacy during the forecast period, 2022-2028. This growth is attributable to the growing advancements in the manufacturing process, increasing application of serine protease among various industrial verticals, and increasing investments by leading players in the product market. Furthermore, the developing countries in the Asia Pacific region are witnessing a significant increase in the demand for serine protease for various applications, including Chemical, Waste management, Food and feed industry, and Silver recovery.
Companies include Novozymes A/S, Jinghai Amino Acid, Solaray, Biocatalysts Limited, Tianan Pharmaceuticals, Associated British Foods, Chemical Amano Enzyme, Jiahe Biotech, Huayang, Bio-Rad Laboratories, Inc., and other prominent players are the key players in the Serine Protease market.
Key Stakeholders
| Report Attribute | Details |
|---|---|
| The revenue forecast in 2028 | USD 4.1 Billion |
| Growth Rate | CAGR of 5.5% from 2022 to 2028. |
| Historical data | 2018 – 2021 |
| Forecast period | 2022 – 2028 |
| Region covered | America, Europe, Asia-Pacific, South America, and Middle East & Africa |
| Key companies Profiled | Novozymes A/S, Jinghai Amino Acid, Solaray, Biocatalysts Limited, Tianan Pharmaceuticals, Associated British Foods, Chemical Amano Enzyme, Jiahe Biotech, Huayang, Bio-Rad Laboratories, Inc., and other prominent players. |
By Type
By Application
By End-Use
By Region
Serine proteases are diverse enzymes characterized by three critical amino acids, histidine, aspartate, and serine, in the catalytic site.
The global Serine Protease market size is forecasted to reach USD 4.1 billion with a CAGR of 5.5% during the forecast period, 2022-2028.
The growing industrialization, growing focus on cost reduction and resource optimization, and increasing application of serine protease in the food industry such as Dietary Supplements and Nutraceuticals, Pharmaceutical, and Industrial such as detergent leather are the primary factors accelerating the growth of the global serine protease market during the forecast period.
The Asia Pacific region is expected to dominate the global Serine Protease market in 2021 and is expected to continue this dominance during the forecast period, 2022-2028.
Companies include Novozymes A/S, Jinghai Amino Acid, Solaray, Biocatalysts Limited, Tianan Pharmaceuticals, Associated British Foods, Chemical Amano Enzyme, Jiahe Biotech, Huayang, Bio-Rad Laboratories, Inc., and other prominent players are the key players in the Serine Protease market.
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